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A nurse holds a vial of Moderna COVID-19 vaccine in Septeme-Les-Vallons, France on Jan. 12, 2022. (Clement Mahoudeau/AFP via Getty Images) The risk of heart inflammation following receipt of a COVID-19 booster shot remains elevated, according to a new study.
The primary series of the messenger RNA-based vaccines, made by Pfizer and Moderna, have already been linked to heart inflammation , but not as much research has been done on whether booster doses also present heart-related risks.
In the study, French researchers analyzed 4,890 myocarditis cases admitted to hospitals in the country between Dec. 27, 2020, and Jan. 31, 2022. They used 48,900 controls from the general population, matching for gender, age, and area of residence.
Receipt of a COVID-19 vaccine booster was found to result in an elevated risk of myocarditis, a type of heart inflammation, particularly receipt of a Moderna booster.
The adjusted risk after a Pfizer booster was three times higher among the boosted, and four times higher after a Moderna booster.
For people aged 12 to 29, the risk was 4.9 times higher for Pfizer booster recipients. Data for young Moderna booster recipients was not available because France suspended use of the vaccine in October 2021, and only made it available again the following month for those over 30 years old.
For those aged 30 and above, a Pfizer booster was associated with a 2.4 times higher risk of heart inflammation, while Moderna’s booster brought a 4.1 times higher risk.
The risks were more elevated if a person received the third dose within 170 days of the first dose. A booster is the third dose because a primary series is comprised of two doses. Similarly, the risk of myocarditis after the second dose is higher in cases where a person receives the dose within 27 days of the first dose.U.S. authorities have […]
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